Ryan Wick's bioinformatics blog
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  • 19 Feb 2025

    FASTQ assemblies with Dorado polish

  • 7 Feb 2025

    Medaka vs Dorado polish

  • 17 Dec 2024

    A first look at CycloneSEQ data

  • 17 Oct 2024

    Medaka v2: progress and potential pitfalls

  • 16 Aug 2024

    Spring OnION: a high-spec laptop for ONT sequencing

  • 31 Jul 2024

    HERRO read correction – part 2

  • 26 Jul 2024

    HERRO read correction – part 1

  • 11 Jun 2024

    Short-read depth recommendations for polishing

  • 8 May 2024

    Duplex basecalling for whole-genome assembly

  • 15 Feb 2024

    A tale of two misassemblies

  • 18 Dec 2023

    Yet another ONT accuracy test: Dorado v0.5.0

  • 9 Dec 2023

    OnION: a high-spec desktop for ONT sequencing

  • 6 Nov 2023

    ONT accuracy vs depth update

  • 24 Oct 2023

    ONT-only accuracy: 5 kHz and Dorado

  • 2 Jun 2023

    Mojo: the future of bioinformatics tools?

  • 15 May 2023

    Short-read polishing of short-read assemblies

  • 5 May 2023

    ONT-only accuracy with R10.4.1

  • 19 Apr 2023

    Viewing tables on the command line

  • 7 Mar 2023

    A perfect bacterial genome from PacBio HiFi reads

  • 21 Feb 2023

    Dead-end count for QC of short-read assemblies

  • 10 Aug 2021

    Oxford Nanopore accuracy vs depth

  • 30 Oct 2020

    Choose-your-own-adventure guide to bacterial genome assembly